Search For A Cure
Scientific Breakthroughs & Caregiver Tips
Depression Brain Science
Current research on major depressive disorder is focused in many different areas, from finding the genetic source of some forms of the disorder to identifying the most effective therapies, both physical and psychological. Scientists are especially interested in understanding more fully the brain chemistry involved in depression so that more effective medications can be developed, particularly for those who don’t respond well to existing drugs.
- The Food and Drug Administration has recently approved the anesthetic ketamine as a treatment for major depression. Scientists were able to develop a form of the well-established drug that can be administered via a nasal spray, and the treatment shows promise for treating medication-resistant depression.
- Researchers are using imaging technologies to take a look at a part of the brain called the hippocampus, which is smaller than normal in some people with depression. It is possible, scientists think, that the hippocampus in these people does not produce enough new nerve cells in the brain, leading to a depressed mood.
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